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Cutting-edge technology from Thuringia sheds light on the basic principles of life

A new invention from Jena has put a smile on the faces of scientists all over the world: An innovative microscope allows gentle three-dimensional imaging of living cells and thus provides deep insights into the basic workings of life. German Federal President Frank-Walter Steinmeier agrees – and so is awarding the 2022 German Future Prize to three researchers at Carl Zeiss Microscopy in Jena: Thomas Kalkbrenner, Jörg Siebenmorgen and Ralf Wolleschensky.

The researchers, working with their teams, have developed a technology that uses high-resolution fluorescence microscopy to examine living objects without disturbing them with light. To achieve this, they built on an existing technology known as lattice light-sheet microscopy, adding innovative optical elements. They also devised a way to make the complex system easy to use and enabled the broad use of common specimen holders. It opens up entirely new avenues for observing and better understanding cellular processes – both in basic research and in the search for new diagnostic methods or novel drugs to target many diseases. In short, Jena is once again living up to its name as a high-tech hub of the optical industry. (gro)

Researchers from Carl Zeiss Microscopy in Jena receive the 2022 German Future Prize.

Award-winning: Researchers from Carl Zeiss Microscopy in Jena receive the 2022 German Future Prize. Photo: Deutscher Zukunftspreis/bildschoen